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  • Pentosan polysulfate sodium is an injectable disease-modifying osteoarthritis drug (DMOAD) used to treat non-infectious and traumatic arthritis in dogs. It is also used off-label in cats. Follow your veterinarian’s instructions on how to administer the injection and dispose of the needle and syringe appropriately. Side effects are rare when given according to label recommendations and at prescribed intervals. Do not use in pets with a known hypersensitivity to it, in pets with known or suspected bleeding disorders or immune-mediated arthritis, or in pets with severe kidney or liver disorders.

  • Pericardial effusion refers to the abnormal accumulation of fluid in the sac surrounding the heart. Pericardial effusion can have a number of underlying causes, including inflammation, infection, cancer, and hereditary defects. Mild cases of pericardial effusion may be asymptomatic, but more significant fluid accumulations can interfere with the heart’s function and lead to severe effects such as sudden death. Treatment and prognosis is dependent upon the underlying cause of the condition.

  • A perineal hernia is a protrusion of tissue through the muscle of the perineum. Potential causes, clinical signs, and treatment are explained. The prognosis ranges from good to poor, depending on the ability to perform surgery and the pet's response to surgery. Perineal hernias have the potential to be life-threatening.

  • Monitoring your pet is important to his health. This handout discusses the use of trackers and apps to monitor your dog's activity level and overall mental and physical health.

  • Prazosin is given by mouth and is used to reduce urinary sphincter tone to relax the bladder and allow easier urination in dogs and cats. It may also be used as a treatment for congestive heart failure, systemic hypertension, or pulmonary hypertension in dogs. Give as directed. Common side effects include lethargy, vomiting, diarrhea, nausea, and constipation. This medication should be used with caution in pets with kidney disease or other conditions that cause low blood pressure, as well as in MDR1-positive dogs. If a negative reaction occurs, contact your veterinarian.

  • Prostatic disease in cats is uncommon and, as a result, relatively little is known about these conditions. Enlargement of the prostate is a common sign with most prostatic diseases and may be noted by your veterinarian on a rectal exam. Other diagnostic tests may be required to determine the cause of your cat's condition.

  • Radiation is a type of energy produced naturally by the sun, earth, and rocks and artificially by machines. Although several types of tumors can be treated with radiation therapy alone (e.g., nasal tumors, brain tumors, and certain types of lymphoma), radiation therapy is most commonly used to destroy or limit the growth of cancer cells left behind (i.e., microscopic disease) after a tumor has been surgically removed. Side effects depend on the type and location of the tumor and its surrounding tissues.

  • A RAST test, or radioallergosorbent test, is a blood test that can be used to determine which allergens are causing a pet's allergies. This test is often performed as part of the workup for atopic dermatitis in cats. The results of allergy testing are typically used to develop a hyposensitization plan for your cat, which helps desensitize your cat to allergens. Many cats treated with hyposensitization, formulated on the basis of RAST results, experience a significant reduction in the signs of allergic dermatitis.

  • The two groups of spiders responsible for most medically significant spider bites include the widow spiders (Latrodectus spp., including the black widow spider) and the recluse spiders (Loxosceles spp., including the brown recluse). The clinical signs and treatment of black widow and brown recluse spider bites vary significantly due to differences in their venom.

  • Home care after surgery mainly involves the restriction of physical activity. Excessive physical activity often leads to injury or serious complications. Monitor the incision daily for signs of redness, swelling, discharge, or excessive licking, and never apply anything to the incision unless instructed to do so. To keep your cat from licking, your veterinarian can provide you with a protective collar or recovery suit. Your cat should gradually improve each day.